Program
| Time |
Event |
(+)
|
|
18:00 - 19:00
|
Discoidin domain receptors: multitaskers for physiological and pathological processes (Ellul) - Birgit Leitinger |
|
|
19:00 - 22:00
|
Cocktail (Room RG ) |
|
| Time |
Event |
(+)
|
|
09:00 - 10:30
|
DDR in molecular and Cellular Biology (Ellul) - Chaired by Frederic Saltel |
|
|
09:00 - 09:40
|
Tumor cell invasion in fibrillar collagen I is mediated by MT1-MMP-based force-producing proteolytic contacts (Ellul) - Philippe Chavrier (Curie institute-France) |
|
|
09:40 - 09:55
|
Regulation of DDR1-Non-Muscle Myosin Interactions and Collagen Contraction are Mediated by Myosin Phosphatase Rho-Interacting Protein (Ellul) - Nuno Coelho |
|
|
09:55 - 10:10
|
Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility (Ellul) - Yoshi Itoh |
|
|
10:10 - 10:25
|
Loss of discoidin domain receptor 1 (DDR1) during kinome rewiring in epithelial-mesenchymal transition (EMT) (Ellul) - Ruby Yun-Ju Huang |
|
|
10:25 - 10:40
|
DDR1 signaling in effector Tcells (Ellul) - Fawzi Aoudjit |
|
|
10:40 - 11:10
|
Coffee break-poster (Room RG ) |
|
|
11:10 - 12:10
|
DDR in physiology and other diseases (Ellul) - chaired by Birgit Leitinger |
|
|
11:10 - 11:25
|
Discoidin Domain Receptor 2 regulates Linear Invadosomes matrix degradation during angiogenesis by recruiting MT1-MMP (Ellul) - Aya Abou Hammoud |
|
|
11:25 - 11:40
|
On the role of DDR1 and DDR2 in the hepatic response to injury (Ellul) - Olaso Elvira |
|
|
11:40 - 11:55
|
Activating mutations in DDR2 cause Warburg-Cinotti syndrome (Ellul) - Bredrup Cecilie |
|
|
11:55 - 12:10
|
TGF-beta1-induced induction of DDR1 involves in myofibroblast activation (Ellul) - Yeh Yi-Chun |
|
|
12:10 - 12:30
|
Commercial session (Ellul) |
|
|
12:30 - 14:00
|
Lunch-poster (Room RG ) |
|
|
14:00 - 16:00
|
DDR in Cancer (session 1) (Ellul) - chaired by Rafael Fridman |
|
|
14:00 - 14:40
|
The metastatic role of DDR1 in colon cancer (Ellul) - Serge Roche |
|
|
14:40 - 14:55
|
DDR1 in Glioblastoma: Resistance mechanisms and therapeutic targeting (Ellul) - Nils Cordes |
|
|
14:55 - 15:10
|
Involvement of discoidin domain receptor 1 and 2 in resistance to the targeted therapy during melanoma (Ellul) - Margaux Sala |
|
|
15:10 - 15:25
|
Discoidin Domain Receptors DDR1 and DDR2 promote matrix-mediated drug resistance (MM-DR) to MAPK-targeting therapies in melanoma (Ellul) - LLona Berestjuk |
|
|
15:25 - 15:40
|
Discoidin Domain Receptor 1 crosstalk with isoform A of Insulin Receptor affects stem-like phenotype in cancer cells (Ellul) - Veronica Vella |
|
|
15:40 - 15:55
|
DDR1 and MT1-MMP expression levels are determinant for triggering BIK-mediated apoptosis by 3D type I collagen matrix in invasive basal-like breast carcinoma cells (Ellul) - Charles Saby |
|
|
16:00 - 16:30
|
Coffee break-poster (Room RG ) |
|
|
16:30 - 18:00
|
DDR in Cancer (session 2) (Ellul) - chaired by Serge Roche |
|
|
16:30 - 17:10
|
Conflicting Pro- and Anti-Malignant Roles of DDRs in Cancer Models: Our Experience Deciphering the Complex Action of DDRs (Ellul) - Rafael Fridman |
|
|
17:10 - 17:25
|
LRP-1 increases colon cancer cell proliferation in 3D culture systems by mediating DDR1 endocytosis (Ellul) - Cao Cuong |
|
|
17:25 - 17:40
|
Implication of DDR1 in renal cell carcinoma development (Ellul) - Patrick Auguste |
|
|
17:40 - 18:00
|
A self-made quiescent ECM niche regulates metastatic dormancy through DDR1 signaling (Ellul) - Bravo-Cordero Javier |
|
|
20:00 - 23:55
|
Gala |
|
| Time |
Event |
(+)
|
|
09:00 - 10:30
|
DDR targeting (Ellul) - chaired by David Santamaria |
|
|
09:30 - 10:10
|
DDR2 and Tumor Mechanobiology (Ellul) - Longmore Gregory |
|
|
10:10 - 10:25
|
Selective Targeting of Discoidin Domain Receptors with Aptamers (Ellul) - Shujaat Ali |
|
|
10:25 - 10:40
|
Pharmaceutical targeting of DDR1 - a 5-year experience (Ellul) - Marco Prunotto |
|
|
10:40 - 11:00
|
Coffee break-poster (Room RG ) |
|
|
11:00 - 12:00
|
DDR perspective in clinic (Ellul) - Chairman Christelle Liard (SIRIC BRIO) François-Xavier Mahon (France, Bergonié Institute, clinician), Nele Vandervoort (Scientist, biomchemical pharmacology, Galapagos), Gregory Longmore (Researcher, USA) and Marco Prunotto (Researcher, Roche, Switzerland), Susana Velasco (researcher CNIO, Spain) |
|
|
12:00 - 12:30
|
Meeting conclusion (Ellul) |
|
|
12:30 - 14:00
|
Lunch (Room RG ) |
|
|
