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09:00 - 10:30
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DDR in molecular and Cellular Biology (Ellul) - Chaired by Frederic Saltel |
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09:00 - 09:40
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Tumor cell invasion in fibrillar collagen I is mediated by MT1-MMP-based force-producing proteolytic contacts (Ellul) - Philippe Chavrier (Curie institute-France) |
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09:40 - 09:55
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Regulation of DDR1-Non-Muscle Myosin Interactions and Collagen Contraction are Mediated by Myosin Phosphatase Rho-Interacting Protein (Ellul) - Nuno Coelho |
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09:55 - 10:10
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Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility (Ellul) - Yoshi Itoh |
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10:10 - 10:25
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Loss of discoidin domain receptor 1 (DDR1) during kinome rewiring in epithelial-mesenchymal transition (EMT) (Ellul) - Ruby Yun-Ju Huang |
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10:25 - 10:40
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DDR1 signaling in effector Tcells (Ellul) - Fawzi Aoudjit |
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10:40 - 11:10
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Coffee break-poster (Room RG ) |
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11:10 - 12:10
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DDR in physiology and other diseases (Ellul) - chaired by Birgit Leitinger |
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11:10 - 11:25
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Discoidin Domain Receptor 2 regulates Linear Invadosomes matrix degradation during angiogenesis by recruiting MT1-MMP (Ellul) - Aya Abou Hammoud |
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11:25 - 11:40
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On the role of DDR1 and DDR2 in the hepatic response to injury (Ellul) - Olaso Elvira |
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11:40 - 11:55
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Activating mutations in DDR2 cause Warburg-Cinotti syndrome (Ellul) - Bredrup Cecilie |
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11:55 - 12:10
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TGF-beta1-induced induction of DDR1 involves in myofibroblast activation (Ellul) - Yeh Yi-Chun |
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12:10 - 12:30
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Commercial session (Ellul) |
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12:30 - 14:00
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Lunch-poster (Room RG ) |
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14:00 - 16:00
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DDR in Cancer (session 1) (Ellul) - chaired by Rafael Fridman |
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14:00 - 14:40
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The metastatic role of DDR1 in colon cancer (Ellul) - Serge Roche |
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14:40 - 14:55
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DDR1 in Glioblastoma: Resistance mechanisms and therapeutic targeting (Ellul) - Nils Cordes |
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14:55 - 15:10
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Involvement of discoidin domain receptor 1 and 2 in resistance to the targeted therapy during melanoma (Ellul) - Margaux Sala |
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15:10 - 15:25
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Discoidin Domain Receptors DDR1 and DDR2 promote matrix-mediated drug resistance (MM-DR) to MAPK-targeting therapies in melanoma (Ellul) - LLona Berestjuk |
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15:25 - 15:40
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Discoidin Domain Receptor 1 crosstalk with isoform A of Insulin Receptor affects stem-like phenotype in cancer cells (Ellul) - Veronica Vella |
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15:40 - 15:55
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DDR1 and MT1-MMP expression levels are determinant for triggering BIK-mediated apoptosis by 3D type I collagen matrix in invasive basal-like breast carcinoma cells (Ellul) - Charles Saby |
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16:00 - 16:30
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Coffee break-poster (Room RG ) |
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16:30 - 18:00
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DDR in Cancer (session 2) (Ellul) - chaired by Serge Roche |
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16:30 - 17:10
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Conflicting Pro- and Anti-Malignant Roles of DDRs in Cancer Models: Our Experience Deciphering the Complex Action of DDRs (Ellul) - Rafael Fridman |
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17:10 - 17:25
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LRP-1 increases colon cancer cell proliferation in 3D culture systems by mediating DDR1 endocytosis (Ellul) - Cao Cuong |
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17:25 - 17:40
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Implication of DDR1 in renal cell carcinoma development (Ellul) - Patrick Auguste |
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17:40 - 18:00
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A self-made quiescent ECM niche regulates metastatic dormancy through DDR1 signaling (Ellul) - Bravo-Cordero Javier |
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20:00 - 23:55
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Gala |
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